Endocrine Abstracts

Introduction: The clinical presentation of a secretory pituitary macroadenoma usually consists of a tumor syndrome accompanied by visual disturbances with signs of pituitary insufficiency and/or hormonal hypersecretion. Herein we describe an unusual presentation of a mixed secretory adenoma.Observation: A 69-year-old was referred to our department for the management of a pituitary macroadenoma revealed by a symptomatology mimicking the Hakim Adams triad ...

Introduction: Glycemic control and weight management are crucial considerations in the treatment of type 2 diabetes (T2D). Liraglutide, an incretin-based therapy, has been demonstrated to not only effectively maintain glycemic control but also promote weight loss in type 2 diabetic patients. Our study aims to evaluate the impact of Liraglutide on body weight and body composition parameters in patients with T2D.Methods: This is a prospective study, carrie...

Introduction: Screening and preventing the onset of degenerative complications of type 2 diabetes is the cornerstone of patients follow up. Recently, new emerging indicators have been suggested to be more sensitive for the early detection of the onset of micro and macroangiopathies. These indicators emerge from the involvement of metabolic syndrome, dyslipidemia and glycemic imbalance in endothelial dysfunction. Among these indicators, we cite the atherogenic index (TC-(HDL-C)...

Introduction: Diabetic retinopathy (DR) is the leading cause of blindness before the age of 50. The etiopathogenesis of DR is still controversial. Even if the microvascular damage is undeniable, the place and importance of the nerve damage must be defined. Our objective was to evaluate the association between DR and diabetic neuropathy (DN) in type 2 diabetics.Methods: It was a cross-sectional, comparative study that included 100 type 2 diabetic patients...

Introduction: Diabetic nephropathy (DN) is a major complication of diabetes and may be fatal at an end stage kidney disease. Several mechanisms lead to the basic lesion of DN (thickening of the glomerular basement membrane) including oxidative stress, inflammation and hyperhomocysteinemia. Being coenzymes of homocysteine metabolism, a deficiency in vitamin B12 and B9 will cause an accumulation of circulating homocysteine. Our objective was to evaluate the association between t...